Copyright 2021 -


Our Publications


Omrani, A., De Vrind, V.A.J., Stoltenborg, I., Kooij, K., Wolterink-Donselaar, I.G., Luijendijk-Berg, M.C.M., Garner, K.M.,
Van't Sant, L.J., Rozeboom, A., Dickson, S.L., Meye, F.J., Adan, R.A.H. (2021).

Identification of novel neurocircuitry through which leptin targets multiple inputs to the dopamine system to reduce food reward seeking. 

Biological Psychiatry [LINK]


Homberg, J.R., et al. ... Genzel, L. (2021).

The continued need for animals to advance brain research. 

Neuron [LINK]


Willems, J., De Jong, A.P.H., Scheefhals, N., Mertens, E., Catsburg, L.A.E., Poorthuis, R.B., De Winter, F., Verhaagen, J.,
Meye, F.J., MacGillavry, H.D. (2020).

ORANGE: A CRISPR/Cas9-based genome editing toolbox for epitope tagging of endogenous proteins in neurons.

PLOS Biology [LINK]


Genzel, L. et al. .... Homberg, J.R. (2020).

How the COVID-19 pandemic highlights the necessity of animal research.

Current Biology [LINK]


Soiza-Reilly, M., Meye, F.J., Olusakin, J., Telley, L., Petit, E., Chen, X., Mameli, M., Jabaudon, D., Sze, J.Y. & Gaspar, P. (2018).

SSRIs target prefrontal to raphe circuits during development modulating synaptic connectivity and emotional behaviour. 

Molecular Psychiatry [LINK]

Tan, D., Nuno-Perez, A., Mameli, M. & Meye, F. J. (2018).

Cocaine withdrawal reduces GABABR transmission at entopeduncular nucleus - lateral habenula synapses.

European Journal of Neuroscience [LINK]


Lecca, S., Meye, F. J., Trusel, M., Tchenio, A., Harris, J., Schwarz, M.K., Georges, F. & Mameli, M.  (2017).

Aversive stimuli drive hypothalamus-to-habenula excitation to promote escape behavior. 

Elife [LINK]

Meye, F. J., Trusel, M., Soiza-Reilly, M. & Mameli, M.  (2017).

Neural circuit adaptations during drug withdrawal - Spotlight on the lateral habenula.

Pharmacology Biochemistry and Behavior [LINK]

Morel, C., Fernandez, S.P., Pantouli, F., Meye, F. J., Marti F., Tolu, S., Parnaudeau, S., Marie, H., Tronche, F., Maskos, U.,
Moretti, M., Gotti, C., Han, M-H., Bailey, A., Mameli, M., Barik, J. & Faure, P. (2017).

Nicotinic receptors mediate stress-nicotine detrimental interplay via dopamine cells’ activity.

Molecular Psychiatry [LINK]


Meye, F. J., Soiza-Reilly, M., Smit, T., Diana, M. A., Schwarz, M. K. & Mameli, M.  (2016).

Shifted pallidal co-release of GABA and glutamate in habenula drives cocaine withdrawal and relapse.

Nature Neuroscience, 19(8):1019-24. [LINK]

Doly, S., Shirvani, H., Gata, G., Meye, F. J., Emerit, MB., Enslen, H., Achour, L., Pardo-Lopez, L., Yang, SK.,
Armand, V., Gardette, R., Giros, B., Gassmann, M., Bettler, B., Mameli, M., Darmon, M., & Marullo, S. (2016).

GABAB receptor cell-surface export is controlled by an endoplasmic reticulum gatekeeper.

Molecular Psychiatry, 21(4):480-90.


Meye, F. J*., Valentinova*, K., Lecca, S*., Marion-Poll, L., Maroteaux, M. J., Musardo, S., Moutkine, I.,
Gardoni, F., Huganir, R., Georges, F. & Mameli, M (2015).

Cocaine-evoked negative symptoms require AMPA receptor trafficking in the lateral habenula.

Nature Neuroscience, 18(3),376-8. [*=equal contribution]

Glangetas C., Fois G.R., Jalabert M., Lecca S., Valentinova K., Meye F. J., Diana M., Faure P., Mameli M., Caille S. & Georges F (2015).

Ventral Subiculum Stimulation Promotes Persistent Hyperactivity of Dopamine Neurons and Facilitates Behavioral Effects of Cocaine.

Cell Reports, 13(10):2287-96.


Meye, F. J., Ramakers, G. M. J. & Adan, R. A. H. (2014).

The vital role of constitutive GPCR activity in the mesolimbic dopamine system.

Translational Psychiatry, 11(4), e361.

Lecca, S., Meye, F. J. & Mameli, M (2014).

The lateral habenula in addiction and depression: an anatomical, synaptic and behavioral overview.

European Journal of Neuroscience, 39(7), 1170-1180.


Meye, F. J., Trezza, V., Vanderschuren, L. J. M. J., Ramakers, G. M. J. & Adan, R. A. H. (2013).

Neutral antagonism for the cannabinoid 1 receptor is a safe tool to treat obesity.

Molecular Psychiatry, 18(12): 1294-1301.

Meye, F. J., Lecca, S., Valentinova, K. & Mameli, M. (2013).

Synaptic and cellular profile of neurons in the lateral habenula.

Frontiers in human neuroscience, 16(7), 870.

Meye, F. J. & Adan, R. A. H. (2013).

Feelings about food: the ventral tegmental area in food reward and emotional eating.

Trends in Pharmacological Sciences, 35(1), 31-40.

Meye, F. J., Van Zessen, R., Smidt, M. P., Adan, R. A. H. & Ramakers, G. M. J (2012).

Morphine withdrawal enhances constitutive mu-opioid receptor activity in the ventral tegmental area.

Journal of Neuroscience, 32(46), 16120-8.